Cloning and Expression of Sheep Renal K-CI Cotransporter-1
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منابع مشابه
Na + - K + - CI - Cotransporter of Brain Capillary Endothelial Cells
Cultured rat brain capillary endothelial cells expressed a large BsRb+ uptake component that was dependent on external Na+ and C1and that was inhibited by loop diuretics with unusual pharmacological properties: benzmetanide (IC, = 1-5 p ~ ) = bumetanide (ICso = 1-5 p ~ ) > piretanide (ICso = 3-16 p ~ ) = furosemide (ICso = 7-11 p ~ ) . It was activated %fold by endothelin-1 (EC, = 1 MI) and end...
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Although K-Cl cotransporter (KCC1) mRNA is expressed in many tissues, K-Cl cotransport activity has been measured in few cell types, and detection of endogenous KCC1 polypeptide has not yet been reported. We have cloned the mouse erythroid KCC1 (mKCC1) cDNA and its flanking genomic regions and mapped the mKCC1 gene to chromosome 8. Three anti-peptide antibodies raised against recombinant mKCC1 ...
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Apolipoprotein CI (ApoCI) belongs to the Apolipoprotein superfamily, members of which are involved in lipid transport, uptake and homeostasis. Excessive ApoCI has been implicated in atherosclerosis and Alzheimer's disease in humans. In this study we report the isolation of Xenopus laevis apoCI and describe the expression pattern of this gene during early development, using reverse transcription...
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Burnham, Charles E., Michael Flagella, Zhaohui Wang, Hassane Amlal, Gary E. Shull, and Manoocher Soleimani. Cloning, renal distribution, and regulation of the rat Na-HCO3 2 cotransporter. Am. J. Physiol. 274 (Renal Physiol. 43): F1119–F1126, 1998.—We recently reported the cloning and expression of a human kidney Na-HCO3 2 cotransporter (NBC-1) (C. E. Burnham, H. Amlal, Z. Wang, G. E. Shull, and...
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The second member of the Na(+)/glucose cotransporter family, SGLT2, is a low-affinity active glucose transporter. In humans, it is predominantly located on the apical membrane of the S1 and S2 segments of renal proximal convoluted tubules, and, thus, may be mainly responsible for the reabsorption of D-glucose from the glomerular filtrate. By BLAST searching the GenBank database, we found expres...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2005
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000087735